A white C. roseus flower Catharanthus roseus, commonly known as bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, is a species of flowering plant in the family Apocynaceae. It was formerly included in the genus Vinca as Vinca rosea. The Gram-positive bacteria were found more sensitive than the Gram-negative bacteria. Some common cultivars are peppermint cooler (white with a red centre), Albus (white flowers), ocellatus group (assorted colours) and Grape Cooler (rose-pink). The results show that C. roseus extracts and fractions are an excellent source of natural antioxidants and could be utilised as a functional food or used for nutraceutical purposes. Rose periwinkle grows well on limestone and sandy soils especially in grassland, woodland or forests. Catharanthus roseus, does an excellent job tolerating the hot temperatures of the summer, and is also able to bear the extremes of drought and heavy rainfall. Madagascar periwinkle is a plant. Periwinkle [Catharanthus roseus (L) G. Don] has become one of the very extensively investigated medicinal plants after the discovery of two powerful anti-cancer alkaloids, vinblastine and vincristine, in its leaves more than 50 years ago.These alkaloidal drugs are still in clinical use. (adsbygoogle = window.adsbygoogle || []).push({});Wound Healing PropertiesNayak et al., (2007) carried out an experiment where rats were treated with 100 mg /kg/day of the Catharanthus roseus ethanol extract. Piperazine citrate was used as the standard reference. These daily supplements have also been deemed effective for preventing and inhibiting the abnormal coagulation of blood in the brain. The plant grows approximately 1 metre tall while the oblong leaves grow between 2.5 to 9 centimetres long and 1 to 3.5 centimetres broad. The roots are also used for treating dysentery. (2011), Evaluation os Hypolipidemic activity of leaf juice of Catharanthus roseus (Linn.) This was followed by treating the diabetic rats with the extract (500mg/kg body weight) daily for 14 consecutive days. In the experiment, group A was the control group, Group B consists of trees that were planted with fungus while Group C consists of trees that were applied with the stems extract together with the fungus. The parts that grow above the ground are used to make medicine. The data on tolerance and on therapy response were evaluated using descriptive statistics. Dichloromethane: methanol (1:1) extract was used for experimenting the in-vitro antibacterial and in-vivo antidiabetic activity. The plant grows approximately 1 metre tall while the oblong leaves grow between 2.5 to 9 centimetres long and 1 to 3.5 centimetres broad. The plant is originally from the Caribbean Basin, West Indies and Madagascar before spreading to other parts of the world such as Africa, Australia, Southern Europe and India where it is mostly grown for commercial purposes due to its high medicinal and ornamental benefits. The leaves are used in folk medicine to control diabetes and high blood pressure. The antibacterial activity was performed using seven different gram positive and gram negative bacterial strains.The extract was reported to contain significant antibacterial action against all the bacterial strains. Best flowering is in summer. It also increases the level of oxygen and glucose level required for the healthy functioning of the brain. Nat Prod 50:586–621.13] Jaleel, C. A., Gopi, R. and Paneerselvam, R. (2009), Alterations in non-enzymatic antioxidant components of Catharanthus roseus exposed to paclobutrazol, gibberellic acid and Pseudomonas fluorescens, Plant Omics Journal, 2: 30-40.14] Zaini, H. M. and Halimoon, N. (2013), Stems Extract of Kemuning cina (Catharanthus roseus) as Biofungicides against White Root Fungal (Rigidoporus microporus) of Rubber Trees (Hevea brasiliensis, Journal of Biofertilizers & Biopesticides, vol.4, issue 2, pp.2-4. (adsbygoogle = window.adsbygoogle || []).push({});Vinblastine is mostly sold as Velban. Vinblastine is mostly sold as Velban. However, only 142 patients completed the trial. Supports the BrainResearchers reveal that the daily supplements produced with the active ingredients present in this plant help to facilitate blood supply to the brain. 3490-3495.5] Fischhof P. K., Moslinger-Gehmayr R., Herrmann W. M., Friedmann A. and Russmann D. L. (1996), Theraupetic efficacy of Vincamine in dementia. 11] Prajakta J. Patil and Jai S. Ghosh. One of such medicinal plants that have received global recognition due to its exceptional benefits is Catharanthus roseus. Subject. ~ In Nigeria and West Indies, the rose periwinkle plant is used for treating diabetes. 183–205.4] Ethalsha, P. and Retna, A. M. (2014), Evaluation of antioxidant potential and antibacterial activity of crude extracts Catharanthus roseus, International journal of Pharmaceutical sciences and research, vol. Medicinal Uses Of Periwinkle Plant Vincristine is another type of alkaloids found in rosy periwinkle that is used for treating. Description. According to Aruna et al., (2015), Catharanthus roseus is used by different countries for treating different diseases for example;(adsbygoogle = window.adsbygoogle || []).push({});~ In Africa, the leaves are used for treating rheumatism (inflammation and pain in the joints) and menorrhagia (abnormally heavy bleeding at menstruation).~ In Madagascar, the leaves are used as vomitive (inducing vomiting), the roots are used as purgative, anthelmintic (for expelling worms), hemostatic (causes bleeding to stop) and for stopping toothache.~ In Malaysia, the plant is used for tackling hypertension, diabetes, cancer and insomnia.~ In India, the leaves extracts are applied on the skin for numbing and neutralising bee sting/ wasp sting. The leaves can also be infused and used for treating menorrhagia (abnormally heavy bleeding at menstruation). Remember to always consult your healthcare provider before making any health-related decisions or for counselling, guidance and treatment about a specific medical condition.REFERENCES1] Agarwal, S., Jacob, S., Chettri, N., Bisoyi, S., Tazeen, A., Vedamurthy, A. Remember to always consult your healthcare provider before making any health-related decisions or for counselling, guidance and treatment about a specific medical condition. Among these 3 groups of rubber trees, only Group C demonstrated the ability of the extract to inhibit the growth of Rigidoporus Microporus. Catharanthus roseus is an important medicinal plant found in various parts of the world and the bioactive compound has been extracted and used as anti-cancer agent to treat the cancer over decades. Herbal use in the Caribbean includes using extracts from the flowers as an eyewash for infants. ~ In Mauritius, the leaves extracts are used for treating indigestion and constipation. Catharanthus roseus is a tropical hardy plant grown as a pot ornamental plant for its rosy or white flowers. Fitoterapia, 78:540-544. It is known for its antitumour, anti-diabetic, anti-microbial, anti-oxidant and anti-mutagenic effects. Don't confuse periwinkle with Madagascar periwinkle (Catharanthus roseus). 68 No. The results support that vincamine has more effects and is superior to placebo in patients with mild to moderate dementia. The compounds include the anti cancer compounds: Vinblastine and Vincristine (Magnotta, 2006). Medicinal Uses Of Periwinkle Plant Study summarizes its properties, advances in decreasing side effects, and new phamaceutical approaches. The leaves also showed significant inhibition against Fusarium moniliforme in the ethanolic extracts. Dichloromethane: methanol (1:1) extract was used for experimenting the in-vitro antibacterial and in-vivo antidiabetic activity. in Guinea pigs, Acta Poloniae Pharmaceutica ñ Drug Research, Vol. Rose periwinkle is very colourful and attractive thus it is an ornamental plant grown for adding beauty to the environment. Don't confuse periwinkle with Madagascar periwinkle (Catharanthus roseus). Histological study of the liver, aorta and kidney was carried out in group 1, 2, 6 and 7 while blood cell count was carried out in animals that were treated with the juice of C. The results show that simultaneous administration of leaf juice of C. roseus in the dosage of 0.5 mL/kg prevents the rise of serum lipid parameters as well as reduces the fatty changes in the tissue induced by the high-fat diet. The alkaloids may also offer sedative and tranquilizing properties. Indeed, a number of activities like antidiabetic, bactericide and antihypertensive are linked to C. roseus.The great pharmacological importance of these indole alkaloids, contrasts with the small amounts of them … Botanical Name: Cantharanthus roseus The corolla bears 5 petal-like lobes and measures between 2 to 5 centimetres in diameter. The flowers are whitish in colour with a yellow midpoint and a basal tube that measures between 2.5 to 3 centimetres long. 10] Patharajan, S. and Abirami, S. A. 3] Cordell G. A., Quinn-Beattie M. L. and Farnsworth N. R. (2001), The potential of alkaloids in drug discovery, Phytother Res 15, pp. Catharanthus roseus is a tropical hardy plant grown as a pot ornamental plant for its rosy or white flowers. Furthermore, the minimum inhibitory concentrations were evaluated for the crude extracts. 1] Agarwal, S., Jacob, S., Chettri, N., Bisoyi, S., Tazeen, A., Vedamurthy, A. 3.Catharanthus Roseus Extract can improve people's memory, thinking ability and mental ability. Despite serious safety … (2010), Antimicrobial Activity of Catharanthus roseus – A Detailed Study. 1-4. (adsbygoogle = window.adsbygoogle || []).push({});Antioxidant EffectsPatharajan and Abirami (2014) assessed the antioxidant effectiveness of Catharanthus roseus leaves extracts and the fractions with solvents of various polarity (water, ethanol, methanol, butanol, acetone and hexane). Catharanthus roseus, does an excellent job tolerating the hot temperatures of the summer, and is also able to bear the extremes of drought and heavy rainfall. I'm Blessing and I'm glad to meet you. It is M phase cell cycle-specific and is an integral component of a plethora of chemo-therapy regimens, including ABVD (Adriamycin, Bleomycin, Vinblastine, Dacarbazine) for Hodgkin’s lymphoma. Studies reveal that most of the vinca alkaloids were first isolated from Catharanthus roseus. In the treatment of testicular carcinomas, vinblastine in association with other antitumor agents often results in a cure rate of over 90% in patients. Many of the vinca alkaloids were first isolated from Catharanthus roseus, including vinblastine and vincristine used in the treatment of leukemia and Hodgkin's lymphoma. Fischhof et al., (1996) investigated the therapeutic effects of vincamine for treating primary degenerative and vascular dementia. 1(2), pp. To. Furthermore, this plant can be quite toxic if excessively consumed orally thus only the recommended dosages should be consumed. Most of these plants also promote general well-being and prolong longevity. Subscribe to Global Food Book's email updates and get a FREE eBook on benefits of organic food. Also, periwinkle is still the only source of these alkaloids and their precursors, catharanthine and vindoline. The alkaloids are prescribed in anticancer therapy, usually as part of complex chemotherapy protocols. The alkaloid vincamine in C roseus keeps blood thin, and is therefore useful in preventing vascular dementia. The potent anticancer compounds are synthesized in shikimate, mevalonate and methyl-erythritol phosphate (MEP) pathways. Synergistic and cytotoxic action of indole alkaloids produced from elicited cell cultures of Catharanthus roseus. The vinca alkaloids impede all fast-dividing cell types including cancer cells. Madagascar periwinkle (Catharanthus roseus L.): Diverse medicinal and therapeutic benefits to humankind @article{Das2017MadagascarP, title={Madagascar periwinkle (Catharanthus roseus L.): Diverse medicinal and therapeutic benefits to humankind}, author={Suddhasuchi Das and A. Adult guinea pigs of either sex were divided into 7 groups. Ethalsha and Retna (2014) examined the antibacterial properties of the crude extracts obtained from the roots of Catharanthus roseus against several bacterial species of clinical significance. The results support the antibacterial and antidiabetic efficacy of the extract thus can be used not only for treating infections but also for treating diabetes. ~ In Philippines, the leaves can be used for treating diabetes and stomach cramps while the root decoction is used for treating intestinal parasitism. Interestingly, most of these medicinal plants are capable of attacking fungal, bacterial and viral infections. Antidiabetic PropertiesDiabetes mellitus is a chronic metabolic disorder marked by hyperglycemia (high blood glucose concentration) due to insulin deficiency and insulin resistance. The fact still remains that most plants offer medicinal supports to tackle several ailments that tend to pose dangers to human beings. Recent years have seen nanotechnology-based synthesis, and these formulations have been considered to increase the efficacy of the bioactive compounds. Catharanthus roseus (L.) G. Don Show All Show Tabs Madagascar periwinkle General Information; Symbol: CARO14 Group: Dicot Family: Apocynaceae Duration: Annual Perennial: Growth Habit: Forb/herb Subshrub: Native Status: HI I L48 I NAV I PB I PR I VI I: Data … Anthelmintic PropertiesAgarwal et al., (2011) evaluated the anthelmintic properties of Catharanthus roseus using Pherithema posthuma (earthworm) as an experimental model. The root bark contains alstonine, serpentine, vincaline I and vincaline II. Join me on this journey to discover, share and grow knowledge on recipes for life from around the globe. Studies on animal models have shown that ethanolic extracts of the leaves and flowers of C. roseus lower blood glucose levels [55]. Don't confuse periwinkle with Madagascar periwinkle (Catharanthus roseus). 1, no. The therapeutic efficacy of vincamine was evidenced by the confirmatory analysis because the drug was statistically significantly superior to placebo in all the four target variables. However, the dose of 1 mL/kg did not only counteracted the elevation, but also significantly (p < 0.05) reduced the serum level LDL-c and the ratio of total cholesterol and HDL-c. Biological control using stems extract of Catharanthus roseus can be used as a healing agent of infected rubber trees. In parts of Central America, it is made into a gargle for sore throats. 152 male and female patients aged between 50 and 85 years from two psychogeriatric centres and two nursing homes were initially included in the trial and screened for eligibility. Catharanthus roseus, commonly called periwinkle, Madagascar periwinkle or annual vinca, is an erect to spreading tender perennial in the dogbane family typically mounding 6-18” (less frequently to 24”) tall and as wide.It produces attractive bushy foliage that is covered by an often profuse bloom of phlox-like flowers from summer to frost. The results support that vincamine has more effects and is superior to placebo in patients with mild to moderate dementia. (adsbygoogle = window.adsbygoogle || []).push({});~ In Mauritius, the leaves extracts are used for treating indigestion and constipation.~ In Jamaica and Cuba, the flower extracts are used as an eyewash for infants.~ In America, the plant is decocted and gargled for easing sore throats and laryngitis. Vinblastine is a component of the regimen of choice for the treatment of metastatic testicular cancer. Chemical Compositions of Catharanthus roseus. The English name periwinkle is shared with the related genus Catharanthus (and also with the common seashore mollusc, Littorina littorea). 927-935.10] Patharajan, S. and Abirami, S. A. Vincristine is mostly sold as oncovin. Published on Mar 20, 2020 PINK PERIWINKLE | Catharanthus roseus is known as ‘tsitsirika’ in the Philippines. Cooking is a passion I developed at a very tender age from my mum and this online platform is where I aim to share and grow knowledge in all things cooking. The parts that grow above the ground are used to make medicine. C. roseus is widely cultivated as an ornamental, but it is also grown for medicinal purposes. 211-213. Contact Gavin Robert McGowen Here, Join the following facebook groups to learn more: Ultimate Weightloss Challenge , Dry Fasting, Longevity Agents , Interstellar Blend Seven Sages, The Infinitely Postive, THE INTERSTELLAR BLEND CHALLENGE: Fluid Restricted Fasting w/ Superherbs. People with tuberculosis, which commonly affects the lungs and causes night sweats and fever, may benefit from using catharanthus roseus. Propagated from cuttings, Soiree brings completely new genetics that offer different looks, as well as distinct benefits to the landscape market. 3490-3495. The oval, hairless, greenish leaves are glossy in appearance with a short petiole that measures between 1 to 1.8 centimetres long. The flowers are also used for treating asthma and excess gas. Cardiovascular disease (CVD) has been classified as the most common cause of death all over the world. The plant produces several flowers such as pink, red, lilac, white and light shade darks. Fitoterapia, 78:540-544.8] Ibrahim, M., SughraMehjabeen, S. and Narsu, M. L. (2011), Pharmacological evaluation of Catharanthus roseus, International Journal of Pharmaceutical Applications ISSN 0976-2639. It was brought into cultivation in the first half of the 18 th century in Paris from seeds collected in Madagascar, and was later distributed from European botanical gardens to … The root part of this plant was extracted in an appropriate solvent followed by the evaluation of the antibacterial effects using agar well diffusion assay against a total of eight bacterial strains. Don't confuse periwinkle with Madagascar periwinkle (Catharanthus roseus). List of various diseases cured by Catharanthus Roseus. It has been used in traditional medicine for thousands of years for treating various diseases and especially it is very famous for it’s use in treating diabetics. Despite serious safety … 6, pp. Today it grows throughout much of the world and plantations have been established on most continents in the warmer climates. The therapeutic efficacy of vincamine was evidenced by the confirmatory analysis because the drug was statistically significantly superior to placebo in all the four target variables. The corolla bears 5 petal-like lobes and measures between 2 to 5 centimetres in diameter. Nat Prod 50:586–621. The vinca alkaloids impede all fast-dividing cell types including cancer cells. The organic extracts demonstrated more significant antifungal activity, unlike the aqueous extracts. The plant is widely used in anticancer therapy and The National Cancer Council of Malaysia (Majlis Kanser National, MAKNA) uses the periwinkle logo as its symbol of hope for cancer patients. Vinblastine and vincristine are the two important bioactive alkaloids produced from this plant. The root part of this plant was extracted in an appropriate solvent followed by the evaluation of the antibacterial effects using agar well diffusion assay against a total of eight bacterial strains.Furthermore, the minimum inhibitory concentrations were evaluated for the crude extracts. Catharanthus roseus (Vinca) Medicinal plant benefits and images. The glossy oval leaves are borne in opposite pairs on slender stems. Neuropsychobiology, 34(1), pp. 4.Catharanthus Roseus Extract has anti-cancer, blood pressure, blood sugar and diuretic effects. B., Krishna, V. and Hoskeri, H. J. Vol 2, Issue 3, pp. C. roseus is commonly known as rosy periwinkle, Vinca Rosea, Cape periwinkle, the Madagascar periwinkle, Kemuning cina, nayantara, vinca-de-madagáscar, vinca del Cabo, rose periwinkle, vinca rosa, tapak dara in Indonesian, vinca rosada, sadaphuli in Marathi, shameless maria (maria-sem-vergonha), roseous vinca in Spanish, Dhafnaki in Greece and İzmir Güzeli in Turkish. in Rose Periwinkle By Blessing Okpala. (2011), Evaluation os Hypolipidemic activity of leaf juice of Catharanthus roseus (Linn.) Diabetes mellitus is a chronic metabolic disorder marked by hyperglycemia (high blood glucose concentration) due to insulin deficiency and insulin resistance. Rosy Periwinkle Health Benefits for Brain. In the study, the stems extracts of Catharanthus roseus were able to reduce the effects of white root diseases. 0 Comments. Furthermore, Quideau et al., (2011) attested that the main active substances in plants are alkaloids, phenolic acids and flavonoids. Furthermore, several biological … 25 Exceptional Benefits of Catharanthus roseus According to Aruna et al., (2015), Catharanthus roseus is used by different countries for treating different diseases for example; ~ In Africa, the leaves are used for treating rheumatism (inflammation and pain in the joints) … especially in children. 5, issue, 8, pp. The plant stems were soaked in dichloromethane (DCM) solution while three batches of rubber trees that consist of five trees were prepared. Different rosy periwinkle cultivars produce different colour shades of flowers such as white, mauve, scarlet, reddish-orange, pink, peach, lavender, lilac and red with a tiny rose-purple, yellowish or reddish central point. (adsbygoogle = window.adsbygoogle || []).push({});In the 12-week double-blind treatment, either 30 mg vincamine or placebo was given twice on a daily basis. This could be opening doors to a new era in the development of nanotechnology-based drugs. Corpus ID: 38654981. The phytochemical analysis of the C. roseus shows that the plant is an excellent source of flavonoids, alkaloids, terpenoids, steroids and other plant secondary metabolites. It produces attractive bushy foliage that is covered by an often profuse bloom of phlox-like flowers from summer to frost. The rosy periwinkle extracts and the fractions contained significant levels of antioxidants at various concentrations. The ethanol extract of this plant also demonstrated to be more effective than the standard drug. Even though the roots and shoots extracts of this plant is poisonous, yet they are used for tackling several diseases especially in the Ayurvedic system of medicine. Soiree, a new collection of catharanthus varieties from Suntory Flowers, revitalizes the genus best known for the familiar bedding plant vinca. The results were compared with the standard drug glibenclamide (5 mg/kg body weight) by measuring the glucose levels and the body weights of all the study animals. … (2014), Antioxidant activity and phytochemical analysis of fractionated leaf extracts of Catharanthus roseus, International Journal of Pharmacognosy, vol. Antifungal PropertiesKumari and Gupta (2013) examined the antifungal properties of Catharanthus roseus against several clinically significant fungal strains namely; Fusarium moniliforme, Candida albicans, Aspergillus niger and Aspergillus fumigatus. , 2006 ) used for stopping excessive bleeding pharmacological activities besides, medicinal plants and its products been! Treatment about a specific medical condition the daily supplements have also been deemed effective for preventing and inhibiting the coagulation., extracts from it have been established on most continents in the ethanolic extracts of kemunting cina were and. 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